ADAM19 antibody (N-Term)

Catalog No. ABIN3044069

Product Details anti-ADAM19 Antibody

Target: ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

Binding Specificity: AA 286-298, N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Disintegrin and metalloproteinase domain-containing protein 19(ADAM19) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequence: RRKLLAQKYH DNA

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Disintegrin and metalloproteinase domain-containing protein 19(ADAM19) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: ADAM metallopeptidase domain 19
Protein Name: Disintegrin and metalloproteinase domain-containing protein 19

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ADAM19(286-298aa RRKLLAQKYHDNA), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADAM19

Target: ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

Alternative Name: ADAM19 (Adam19 Products)

Synonyms: AL024287 antibody, M[b] antibody, Mltnb antibody, MADDAM antibody, MLTNB antibody, Sox30 antibody, fksg34 antibody, maddam antibody, mltnb antibody, a disintegrin and metallopeptidase domain 19 (meltrin beta) antibody, ADAM metallopeptidase domain 19 antibody, ADAM metallopeptidase domain 19 S homeolog antibody, Adam19 antibody, ADAM19 antibody, adam19.S antibody

Background: ADAM19(A Disintegrin and Metalloproteinase Domain 19), also known as MLTNB, is a human gene. This gene encodes a member of the ADAM(a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Hirohata et al.(1998) used radiation hybrids to map ADAM19 to mouse chromosome 11 and to human chromosome 5q32-q33.

Synonyms: A disintegrin and metalloproteinase domain 19(meltrin beta) antibody|A disintegrin and metalloproteinase domain 19 antibody|ADAM 19 antibody|ADAM metallopeptidase domain 19 antibody|Disintegrin and metalloproteinase domain containing protein 19 antibody|FKSG 34 antibody|FKSG34 antibody|MADDAM antibody|Meltrin beta antibody|Metalloprotease and disintegrin dentritic antigen marker antibody|MLTN B antibody|MLTNB antibody

UniProt: Q9H013