CCL1 antibody (AA 24-96)

Catalog No. ABIN3043738

Product Details anti-CCL1 Antibody

Target: CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

Binding Specificity: AA 24-96

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit IgG polyclonal antibody for C-C motif chemokine 1(CCL1) detection. Tested with WB, ELISA in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for C-C motif chemokine 1(CCL1) detection. Tested with WB, ELISA in Human.
Gene Name: chemokine (C-C motif) ligand 1
Protein Name: C-C motif chemokine 1

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human I-309 recombinant protein (Position: K24-K96). Human I-309 shares 38% amino acid (aa) sequence identity with mouse I-309.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for I-309 is approximately 0.25 ng/lane under reducing conditions.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-CCL1 antibody (ABIN3043738)

Li, Chen, Liu, Hou: "Long-pulse gastric electrical stimulation protects interstitial cells of Cajal in diabetic rats via IGF-1 signaling pathway." in: World journal of gastroenterology, Vol. 22, Issue 23, pp. 5353-63, (2017) (PubMed).

Hou, Wan, Wang, Li, Wang, Yao, Feng, Jing, Lu, Jia, Peng: "Let-7a inhibits migration of melanoma cells via down-regulation of HMGA2 expression." in: American journal of translational research, Vol. 8, Issue 9, pp. 3656-3665, (2016) (PubMed).

Liang, Hao, Zhang, Wu, Wang: "Insulin-like growth factors in endometrioid adenocarcinoma: correlation with clinico-pathological features and estrogen receptor expression." in: BMC cancer, Vol. 12, pp. 262, (2013) (PubMed).

Zhang, Leng, Wang, Zhang: "Treating human meniscal fibrochondrocytes with hIGF-1 gene by liposome." in: Clinical orthopaedics and related research, Vol. 467, Issue 12, pp. 3175-82, (2010) (PubMed).

Target Details for CCL1

Target: CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

Alternative Name: CCL1 (CCL1 Products)

Synonyms: I-309 antibody, P500 antibody, SCYA1 antibody, SISe antibody, TCA3 antibody, BF534335 antibody, Scya1 antibody, Tca-3 antibody, CCLi6 antibody, chemokine antibody, C-C motif chemokine ligand 1 antibody, chemokine (C-C motif) ligand 1 antibody, CCL1 antibody, Ccl1 antibody

Background: CCL1, Chemokine (C-C motif) ligand 1, is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8.

Synonyms: C-C motif chemokine 1 antibody|Ccl1 antibody|CCL1_HUMAN antibody|Chemokine CC Motif Ligand 1 antibody|inflammatory cytokine I-309 antibody|P500 antibody|SCYA1 antibody|SISe antibody|small inducible cytokine A1 antibody|Small-inducible cytokine A1 antibody|T lymphocyte secreted protein I-309 antibody|T lymphocyte-secreted protein I-309 antibody|TCA3 antibody

Gene ID: 6346

UniProt: P22362