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POR antibody (C-Term)

POR Reactivity: Human, Rat, Mouse WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043443
  • Target See all POR Antibodies
    POR (P450 (Cytochrome) Oxidoreductase (POR))
    Binding Specificity
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 633-668, C-Term
    Reactivity
    • 48
    • 33
    • 28
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 46
    • 6
    • 2
    • 1
    Rabbit
    Clonality
    • 43
    • 12
    Polyclonal
    Conjugate
    • 33
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This POR antibody is un-conjugated
    Application
    • 36
    • 19
    • 11
    • 10
    • 10
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for NADPH--cytochrome P450 reductase(POR) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequence
    RNMARDVQNT FYDIVAELGA MEHAQAVDYI KKLMTK
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for NADPH--cytochrome P450 reductase(POR) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: P450 (cytochrome) oxidoreductase
    Protein Name: NADPH--cytochrome P450 reductase
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human POR (633-668aa RNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTK), different from the related mouse and rat sequences by five amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product POR Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    POR (P450 (Cytochrome) Oxidoreductase (POR))
    Alternative Name
    POR (POR Products)
    Synonyms
    CPR antibody, CYPOR antibody, P450R antibody, POR antibody, CCR antibody, CG11567 antibody, DMR antibody, DmCPR antibody, Dmel\\CG11567 antibody, NCPR antibody, P450 antibody, cpr antibody, zgc:110032 antibody, npr antibody, xpor antibody, 4933424M13Rik antibody, PORCINO antibody, T5J17.90 antibody, T5J17_90 antibody, TFC C antibody, TUBULIN-FOLDING COFACTOR C antibody, cytochrome p450 oxidoreductase antibody, P450 (cytochrome) oxidoreductase antibody, ADP-ribosylation factor interacting protein 2 antibody, Cytochrome P450 reductase antibody, P450 (cytochrome) oxidoreductase a antibody, P450 (cytochrome) oxidoreductase L homeolog antibody, NADPH--cytochrome P450 reductase antibody, C-CAP/cofactor C-like domain-containing protein antibody, POR antibody, Arfip2 antibody, Por antibody, Cpr antibody, pora antibody, por.L antibody, LOC100406157 antibody, por antibody, LOC100619047 antibody
    Background
    POR is a membrane-boundenzyme required for electron transfer from NADPH to cytochrome P450 in the endoplasmic reticulum of theeukaryotic cell. The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

    Synonyms: CPR antibody|CYPOR antibody|DKFZp686G04235 antibody|FLJ26468 antibody|NADPH Cytochrome P450 Reductase antibody|NADPH dependent cytochrome P450 reductase antibody|NADPH--cytochrome P450 reductase antibody|NCPR_HUMAN antibody|P450 (cytochrome) oxidoreductase antibody|P450 Cytochrome Oxidoreductase antibody|P450R antibody|POR antibody
    Gene ID
    5447
    UniProt
    P16435
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
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