SNAI3 antibody (Middle Region)

Catalog No. ABIN3043345

Product Details anti-SNAI3 Antibody

Target: SNAI3 (Snail Homolog 3 (SNAI3))

Binding Specificity: AA 155-178, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAI3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Zinc finger protein SNAI3(SNAI3) detection. Tested with WB in Human.

Sequence: FHCHKPYHTL AGLARHRQLH CHLQ

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Zinc finger protein SNAI3(SNAI3) detection. Tested with WB in Human.
Gene Name: snail family zinc finger 3
Protein Name: Zinc finger protein SNAI3

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SNAI3 (155-178aa FHCHKPYHTLAGLARHRQLHCHLQ), different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SNAI3 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for SNAI3

Target: SNAI3 (Snail Homolog 3 (SNAI3))

Alternative Name: SNAI3 (SNAI3 Products)

Synonyms: SMUC antibody, SNAIL3 antibody, ZNF293 antibody, Zfp293 antibody, AI643946 antibody, Smuc antibody, snail family transcriptional repressor 3 antibody, snail family zinc finger 3 antibody, SNAI3 antibody, Snai3 antibody

Background: SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis. SNAI3 gene, was located between KIAA0233 gene and CBFA2T3 gene in human chromosome 16q24.3, a region affected in breast cancer, gastric cancer, hepatocellular carcinoma, ovarian cancer, and therapy-related myeloid leukemia with t(16,21)(q24,q22) translocation. Human SNAI3 gene was found to encode 292-amino-acid polypeptide with the N-terminal SNAG domain and five zinc finger domains. And Human SNAI3 mRNA was expressed in skin melanotic melanoma, lung epidermoid carcinoma, and germ cell tumor. Because SNAG zinc-finger proteins are transcriptional repressors implicated in carcinogenesis and embryogenesis, SNAI3 gene might be a potent target of pharmacogenomics in the field of oncology and regenerative medicine.

Synonyms: MGC129606 antibody|Protein snail homolog 3 antibody|SMUC antibody|SNAI3 antibody|SNAI3_ HUMAN antibody|Snail homolog 3 (Drosophila) antibody|SNAIL3 antibody|Zfp293 antibody|Zinc finger protein 293 antibody|Zinc finger protein SNAI3 antibody|ZNF293 antibody

Gene ID: 333929