beta Defensin 1 antibody (C-Term)

Catalog No. ABIN3043211

Product Details anti-beta Defensin 1 Antibody

Target: beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

Binding Specificity: AA 52-68, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Defensin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Beta-defensin 1(DEFB1) detection. Tested with WB, IHC-P in Human.

Sequence: FTKIQGTCYR GKAKCCK

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Beta-defensin 1(DEFB1) detection. Tested with WB, IHC-P in Human.
Gene Name: defensin, beta 1
Protein Name: Beta-defensin 1(BD-1/hBD-1)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human beta Defensin 1(52-68aa FTKIQGTCYRGKAKCCK).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for beta Defensin 1

Target: beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

Alternative Name: DEFB1 (DEFB1 Products)

Synonyms: BD1 antibody, DEFB-1 antibody, DEFB101 antibody, HBD1 antibody, AW260221 antibody, BD-1 antibody, DEFB1-like antibody, RHBD-1 antibody, CBD1 antibody, PBD-1 antibody, DEFB1 antibody, BNBD-1 antibody, defensin beta 1 antibody, avian beta-defensin 1 antibody, defensin, beta 1 antibody, beta-defensin 1-like antibody, beta-defensin 1 antibody, DEFB1 antibody, Defb1 antibody, AvBD1 antibody, LOC100861170 antibody

Background: DEFB1,Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.

Synonyms: BD 1 antibody|BD-1 antibody|BD1 antibody|beta 1 antibody|Beta defensin 1 antibody|Beta-defensin 1 antibody|DEFB 1 antibody|DEFB1 antibody|DEFB1_HUMAN antibody|DEFB101 antibody|Defensin antibody|Defensin beta 1 antibody|Defensin beta 1 preproprotein antibody|HBD 1 antibody|hBD-1 antibody|HBD1 antibody|MGC51822 antibody

UniProt: P60022