TNNC1 antibody (N-Term)

Catalog No. ABIN3043055

Product Details anti-TNNC1 Antibody

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Binding Specificity: AA 1-18, N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Troponin C, slow skeletal and cardiac muscles(TNNC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequence: MDDIYKAAVE QLTEEQKN

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Troponin C, slow skeletal and cardiac muscles(TNNC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: troponin C type 1(slow)
Protein Name: Troponin C, slow skeletal and cardiac muscles

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human cardiac Troponin C(1-18aa MDDIYKAAVEQLTEEQKN), identical to the related rat and mouse sequences .

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TNNC1

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Alternative Name: TNNC1 (TNNC1 Products)

Synonyms: CMD1Z antibody, CMH13 antibody, TN-C antibody, TNC antibody, TNNC antibody, cTnC antibody, tnnc1 antibody, zgc:103465 antibody, PCTNC1 antibody, cmd1z antibody, cmh13 antibody, tnc antibody, tnnc antibody, MGC80066 antibody, TNNC1 antibody, AI874626 antibody, TnC antibody, cTnI antibody, tncc antibody, Tncc antibody, stnnc antibody, zgc:86932 antibody, troponin C1, slow skeletal and cardiac type antibody, troponin C type 1a (slow) antibody, troponin C type 1 (slow) L homeolog antibody, cardiac troponin C antibody, troponin C, cardiac/slow skeletal antibody, troponin C type 1b (slow) antibody, TNNC1 antibody, tnnc1a antibody, tnnc1.L antibody, tnnc1 antibody, Tnnc1 antibody, tnnc1b antibody

Background: Troponin C1(TNNC1)(troponin C type 1(slow)), also called TROPONIN C, SLOW-TWITCH SKELETAL MUSCLE or TNC, is a protein that in humans is encoded by the TNNC1 gene. Using a "monochromosomal" hybrid panel, the TNNC1 gene is mapped to chromosome 3, subsequent analysis of the Genebridge 4 radiation hybrid panel localized the gene to 3p in a region consistent with the earlier assignment. Circular dichroism measurements revealed changes in the secondary structures of the TNNC1 mutants A8V, C84Y, and D145E.

Synonyms: tnnc1a antibody|Cardiac troponin C antibody|CMH7 antibody|cTnI antibody|slow skeletal and cardiac muscles antibody|Slow troponin C1 antibody|TN C antibody|TN-C antibody|TNC antibody|TNNC 1 antibody|TNNC antibody|TNNC1 antibody|TNNC1 protein antibody|TNNC1_HUMAN antibody|TNNI3 antibody|Troponin C antibody|Troponin C cardiac antibody|Troponin C slow antibody|Troponin C slow skeletal and cardiac muscles antibody|Troponin C type 1(slow) antibody|Troponin C type 1 antibody|Troponin C1 slow antibody|Troponin I type 3(cardiac) antibody

UniProt: P63316