TLR10 antibody (N-Term)

Catalog No. ABIN3042981

Product Details anti-TLR10 Antibody

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Binding Specificity: AA 88-102, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR10 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Toll-like receptor 10(TLR10) detection. Tested with WB in Human.

Sequence: DLKTFEFNKE LRYLD

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Toll-like receptor 10(TLR10) detection. Tested with WB in Human.
Gene Name: toll-like receptor 10
Protein Name: Toll-like receptor 10

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TLR10(88-102aa DLKTFEFNKELRYLD).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for TLR10 is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TLR10

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Alternative Name: TLR10 (TLR10 Products)

Synonyms: TLR10 antibody, CD290 antibody, toll like receptor 10 antibody, toll-like receptor 10 antibody, TLR10 antibody, Tlr10 antibody

Background: TLR10(Toll-like receptor 10), is a protein that in humans is encoded by the TLR10 gene. The protein encoded by this gene is a member of the Toll-like receptor(TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. By genomic sequence analysis, Hasan et al.(2005) determined that the TLR10 gene is clustered with TLR1 and TLR6 on chromosome 4p14. By coimmunoprecipitation analysis, Hasan et al.(2005) found that TLR10 associated with itself and with TLR1 and TLR2, but not with MD2. Signaling studies showed that TLR10 required MYD88, but not TIRAP, TRAM(TICAM2), or TRIF(TICAM1), to activate immune system promoters. Pro674 within the TLR10 TIR domain was required to activate all promoter examined.

Synonyms: CD 290 antibody|CD 290 antigen antibody|CD290 antibody|CD290 antigen antibody|MGC104967 antibody|MGC126398 antibody|MGC126399 antibody|OTTHUMP00000158729 antibody|OTTHUMP00000218162 antibody|TLR10 antibody|TLR10_HUMAN antibody|Toll like receptor 10 antibody|Toll-like receptor 10 antibody|UNQ315/PRO358 antibody

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades