Interferon gamma antibody (AA 24-166)
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- Target See all Interferon gamma (IFNG) Antibodies
- Interferon gamma (IFNG)
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Binding Specificity
- AA 24-166
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Interferon gamma antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Interferon gamma(IFNG) detection. Tested with WB, IHC-P, ELISA in Human.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Interferon gamma(IFNG) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: Interferon gamma
Protein Name: Interferon gamma(IFN-gamma) - Purification
- Immunogen affinity purified.
- Immunogen
- E. coli-derived human IFN gamma recombinant protein(Position: Q24-Q166).
- Isotype
- IgG
- Top Product
- Discover our top product IFNG Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Species: Human
Notes: Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Expiry Date
- 12 months
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Tangshen Formula Attenuates Colonic Structure Remodeling in Type 2 Diabetic Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 4064156, (2017) (PubMed).
: "Women with recurrent spontaneous abortion have decreased 25(OH) vitamin D and VDR at the fetal-maternal interface." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, Vol. 50, Issue 11, pp. e6527, (2017) (PubMed).
: "Somatostatin Improved B Cells Mature in Macaques during Intestinal Ischemia-Reperfusion." in: PLoS ONE, Vol. 10, Issue 7, pp. e0133692, (2016) (PubMed).
: "Protective effect of carnosine after chronic cerebral hypoperfusion possibly through suppressing astrocyte activation." in: American journal of translational research, Vol. 7, Issue 12, pp. 2706-15, (2016) (PubMed).
: "HPV16L1-attenuated Shigella recombinant vaccine induced strong vaginal and systemic immune responses in guinea pig model." in: Human vaccines & immunotherapeutics, Vol. 10, Issue 12, pp. 3491-8, (2015) (PubMed).
: "Somatostatin inhibits the production of interferon-γ by intestinal epithelial cells during intestinal ischemia-reperfusion in macaques." in: Digestive diseases and sciences, Vol. 59, Issue 10, pp. 2423-32, (2014) (PubMed).
: "
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Tangshen Formula Attenuates Colonic Structure Remodeling in Type 2 Diabetic Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 4064156, (2017) (PubMed).
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- Target
- Interferon gamma (IFNG)
- Alternative Name
- IFNG (IFNG Products)
- Synonyms
- IFG antibody, IFI antibody, IFN-g antibody, Ifg antibody, IFNG2 antibody, IFN-gamma antibody, IFN-G antibody, IFNG antibody, IFNgamma antibody, TCRalpha antibody, INF-G antibody, ifng antibody, interferon gamma antibody, interferon, gamma 1-2 antibody, IFNG antibody, Ifng antibody, ifng1-2 antibody
- Background
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Interferon-gamma(IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-gamma is also produced by natural killer(NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis. IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions. IFN-gamma plays an important role in the control of neointima proliferation.
Synonyms: IFG antibody|IFI antibody|IFN Gamma antibody|IFN Immune antibody|IFN-gamma antibody|IFNG antibody|Immune Interferon antibody|Interferon gamma antibody|Interferon Gamma Precursor antibody|Macrophage Activating Factor antibody|MAF antibody|T Cell Interferon antibody|Type II Interferon antibody - UniProt
- P01579
- Pathways
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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