APCS antibody (AA 21-224)
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- Target See all APCS Antibodies
- APCS (Amyloid P Component, Serum (APCS))
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Binding Specificity
- AA 21-224
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APCS antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Serum amyloid P-component(APCS) detection. Tested with WB, IHC-P, ELISA in Mouse.
- Brand
- Picoband™
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Serum amyloid P-component(APCS) detection. Tested with WB, IHC-P, ELISA in Mouse.
Gene Name: amyloid P component, serum
Protein Name: Serum amyloid P-component - Purification
- Immunogen affinity purified.
- Immunogen
- E.coli-derived mouse Serum Amyloid P recombinant protein (Position: Q21-D224). Mouse Serum Amyloid P shares 70% and 80% amino acid (aa) sequences identity with human and rat Serum Amyloid P, respectively.
- Isotype
- IgG
- Top Product
- Discover our top product APCS Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- APCS (Amyloid P Component, Serum (APCS))
- Alternative Name
- APCS (APCS Products)
- Synonyms
- PTX2 antibody, SAP antibody, Sap antibody, APCS antibody, FP antibody, SAP(FP) antibody, apcs antibody, ptx2 antibody, sap antibody, amyloid P component, serum antibody, serum amyloid P-component antibody, amyloid P component, serum protein L homeolog antibody, APCS antibody, Apcs antibody, apcs.L antibody
- Background
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Amyloid P component, serum(SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component(AP), a 25 kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened beta-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Synonyms: 9.5S alpha 1 glycoprotein antibody|9.5S alpha-1-glycoprotein antibody|Amyloid P component serum antibody|APCS antibody|MGC88159 antibody|Pentaxin related antibody|Pentraxin 2 antibody|PTX 2 antibody|PTX2 antibody|SAMP_HUMAN antibody|SAP antibody|Serum amyloid P component antibody|Serum amyloid P-component(1-203) antibody - Gene ID
- 20219
- UniProt
- P12246
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