KLF6 antibody (AA 38-205)

Catalog No. ABIN3042475

Product Details anti-KLF6 Antibody

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Binding Specificity: AA 38-205

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF6 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Krueppel-like factor 6(KLF6) detection. Tested with WB in Human,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Krueppel-like factor 6(KLF6) detection. Tested with WB in Human,Rat.
Gene Name: Kruppel-like factor 6
Protein Name: Krueppel-like factor 6

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human KLF6 recombinant protein (Position: E38-N205). Human KLF6 shares 92% and 90% amino acid (aa) sequences identity with mouse and rat KLF6, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for KLF6 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for KLF6

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Alternative Name: KLF6 (KLF6 Products)

Synonyms: gbf antibody, zf9 antibody, bcd1 antibody, cba1 antibody, cpbp antibody, pac1 antibody, st12 antibody, copeb antibody, MGC53475 antibody, KLF6 antibody, MGC127307 antibody, BCD1 antibody, CBA1 antibody, COPEB antibody, CPBP antibody, GBF antibody, PAC1 antibody, ST12 antibody, ZF9 antibody, AI448727 antibody, C86813 antibody, Copeb antibody, FM2 antibody, FM6 antibody, Ierepo1 antibody, Ierepo3 antibody, R75280 antibody, Zf9 antibody, Aa1017 antibody, klf6 antibody, cb538 antibody, wu:fb76d04 antibody, wu:fb92h03 antibody, wu:fe26g06 antibody, wu:fk78f12 antibody, Kruppel-like factor 6 L homeolog antibody, Kruppel like factor 6 antibody, Krueppel-like factor 6 antibody, Kruppel-like factor 6 antibody, Kruppel-like factor 6 S homeolog antibody, Kruppel-like factor 6a antibody, klf6.L antibody, KLF6 antibody, LOC100196412 antibody, klf6 antibody, Klf6 antibody, klf6.S antibody, klf6a antibody

Background: Krueppel-like factor 6 (KLF6) is a protein that in humans is encoded by the KLF6 gene. It is a tumor suppressor gene which is located on 10p15.1. This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.

Synonyms: B cell derived protein 1 antibody|B cell-derived 1 antibody|B-cell-derived protein 1 antibody|BCD1 antibody|CBA1 antibody|COPEB antibody|Core promoter element-binding protein antibody|CPBP antibody|GBF antibody|GC rich binding factor antibody|GC rich sites binding factor GBF antibody|GC-rich sites-binding factor GBF antibody|Klf6 antibody|KLF6_HUMAN antibody|Krueppel-like factor 6 antibody|Krueppel-like factor 6 isoform C antibody|Kruppel like zinc finger protein Zf9 antibody|PAC1 antibody|Proto-oncogene BCD1 antibody|Protooncogene B cell derived 1 antibody|ST12 antibody|Suppression of tumorigenicity 12 (prostate) antibody|Suppressor of tumorigenicity 12 protein antibody|Transcription factor Zf9 antibody|Zf9 antibody

Gene ID: 1316

UniProt: Q99612