HMOX2 antibody (AA 2-316)

Catalog No. ABIN3042450

Product Details anti-HMOX2 Antibody

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Binding Specificity: AA 2-316

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMOX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Heme oxygenase 2(HMOX2) detection. Tested with WB, IHC-P in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Heme oxygenase 2(HMOX2) detection. Tested with WB, IHC-P in Human.
Gene Name: heme oxygenase (decycling) 2
Protein Name: Heme oxygenase 2

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HMOX2 recombinant protein (Position: S2-M316). Human HMOX2 shares 89% and 90% amino acid (aa) sequences identity with mouse and rat HMOX2, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for HMOX2 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for HMOX2

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Alternative Name: HMOX2 (HMOX2 Products)

Synonyms: HO-2 antibody, HO2 antibody, HMOX2 antibody, Ho-2 antibody, im:6909100 antibody, si:dkey-44g23.7 antibody, AtHO2 antibody, T9J22.22 antibody, T9J22_22 antibody, heme oxygenase 2 antibody, hmox2 antibody, ho-2 antibody, heme oxygenase 2 antibody, Heme oxygenase 2 antibody, heme oxygenase 2, putative antibody, heme oxygenase 2a antibody, heme oxygenase 2 L homeolog antibody, HMOX2 antibody, Hmox2 antibody, HO2 antibody, ho2 antibody, CNF01200 antibody, CPR_0203 antibody, CGB_F5120W antibody, hmox2a antibody, hmox2.L antibody

Background: Heme oxygenase 2 (HMOX2), also known as HO-2, is an enzyme that in humans is encoded by the HMOX2 gene. It is mapped to 16p13.3. HMOX2 belongs to the heme oxygenase family. Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

Synonyms: Heme oxygenase (decycling) 2 antibody|Heme oxygenase (decyclizing) 2 antibody|Heme oxygenase 2 antibody|HMOX 2 antibody|HMOX2 antibody|HMOX2 protein antibody|HMOX2_HUMAN antibody|HO 2 antibody|HO-2 antibody|HO2 antibody|OTTHUMP00000159847 antibody|

Gene ID: 3163

UniProt: P30519

Pathways: Transition Metal Ion Homeostasis