FZD1 antibody (C-Term)

Catalog No. ABIN3042412

Product Details anti-FZD1 Antibody

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Binding Specificity: AA 369-400, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Frizzled-1(FZD1) detection. Tested with WB, IHC-P in Human.

Sequence: YIAGFLLEDR VVCNDKFAED GARTVAQG

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Frizzled-1(FZD1) detection. Tested with WB, IHC-P in Human.
Gene Name: frizzled class receptor 1
Protein Name: Frizzled-1

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Frizzled homolog 1 (369-400aa YIAGFLLEDRVVCNDKFAEDGARTVAQG TKKE), identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.6 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-2 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for FZD1

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Alternative Name: FZD1 (Fzd1 Products)

Synonyms: CG17697 antibody, CG3646 antibody, DFZ1 antibody, DFz antibody, DFz1 antibody, Dfz1 antibody, Dm Fz1 antibody, Dmel\\CG17697 antibody, FZ antibody, Frz antibody, Fz antibody, Fz1 antibody, frz antibody, fz1 antibody, fz[[1]] antibody, Fz-1 antibody, cFz-1 antibody, Xfrizzled-1 antibody, frizzled1 antibody, frz-1 antibody, frz1 antibody, fzd1-A antibody, AW227548 antibody, FZ-1 antibody, frizzled antibody, frizzled class receptor 1 antibody, frizzled class receptor 1 L homeolog antibody, fz antibody, FZD1 antibody, Fzd1 antibody, fzd1.L antibody

Background: Frizzled-1 (Frizzled homolog 1) is a protein that in humans is encoded by the FZD1 gene. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signalingproteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.

Synonyms: Chfz-1 antibody|Dfrizzled-1 antibody|DKFZp564G072 antibody|FLJ95923 antibody|Frizzled 1 antibody|Frizzled homolog 1 (Drosophila) antibody|Frizzled homolog 1 antibody|Frizzled-1 antibody|Fz receptor 1 antibody|Fz-1 antibody|Fz1 antibody|FZD1 antibody|FZD1_HUMAN antibody|FzE1 antibody|hFz1 antibody|Rfz1 antibody|Wnt receptor antibody|Xfrizzled-1 antibody

Gene ID: 8321

Pathways: WNT Signaling, Asymmetric Protein Localization