FSHB antibody (AA 19-129)

Catalog No. ABIN3042408

This anti-FSHB antibody is a Rabbit Polyclonal antibody detecting FSHB in WB and IHC. Suitable for Human and Mouse.

Quick Overview for FSHB antibody (AA 19-129) (ABIN3042408)

Target: FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FSHB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FSHB Antibody

Binding Specificity: AA 19-129

Purpose: Anti-FSH beta/FSHB Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-FSH beta/FSHB Antibody Picoband® (ABIN3042408). Tested in IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FSH beta recombinant protein (Position: N19-E129). Human FSH beta shares 90% and 89% amino acid (aa) sequences identity with mouse and rat FSH beta, respectively.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse
Western blot, 0.1-0.5 μg/mL, Human
1. He, C. H., Gong, P., Hu, B., Stewart, D., Choi, M. E., Choi, A. M. K., Alam, J.Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein: implication for heme oxygenase-1 gene regulation. J. Biol. Chem. 276: 20858-20865, 2001. 2. Piantadosi CA, Withers CM, Bartz RR, MacGarvey NC, Fu P, Sweeney TE, Welty-Wolf KE, Suliman HB (May 2011). "Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression". J. Biol. Chem.286 (18): 16374-85.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for FSHB

Target: FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

Alternative Name: FSHB

Background:

Synonyms: Follitropin subunit beta,Follicle-stimulating hormone beta subunit,FSH-B,FSH-beta,Follitropin beta chain,FSHB,

Background: FSHB, also known as Follitropin subunit beta, is a protein that in humans is encoded by the FSHB gene, and this gene is mapped to 11p14.1. FSHB enables ovarian folliculogenesis to the antral follicle stage and is essential for Sertoli cell proliferation and maintenance of sperm quality in the testis. It can stimulate development of follicle and spermatogenesis in the reproductive organs. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production.

Sequence Similarities: Belongs to the glycoprotein hormones subunit beta family.

Molecular Weight: 36 kDa

Gene ID: 2488

UniProt: P01225

Pathways: Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process