FSHB antibody (AA 19-129)

Catalog No. ABIN3042408

Product Details anti-FSHB Antibody

Target: FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

Binding Specificity: AA 19-129

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FSHB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Follitropin subunit beta(FSHB) detection. Tested with WB, IHC-P in Human,Mouse.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Follitropin subunit beta(FSHB) detection. Tested with WB, IHC-P in Human,Mouse.
Gene Name: follicle stimulating hormone, beta polypeptide
Protein Name: Follitropin subunit beta

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FSH beta recombinant protein (Position: N19-E129). Human FSH beta shares 90% and 89% amino acid (aa) sequences identity with mouse and rat FSH beta, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for FSH beta is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for FSHB

Target: FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

Alternative Name: FSHB (FSHB Products)

Synonyms: gthI antibody, fsh-beta antibody, LOC100136594 antibody, FSHB antibody, LOC100218526 antibody, FSH antibody, Fshbeta antibody, FSH-beta antibody, follicle stimulating hormone, beta polypeptide antibody, follicle stimulating hormone beta subunit L homeolog antibody, follcle-stimulating hormone beta subunit antibody, follicle stimulating hormone beta subunit antibody, follicle stimulating hormone beta antibody, follitropin subunit beta antibody, fshb antibody, fshb.L antibody, LOC100136594 antibody, FSHB antibody, Fshb antibody

Background: FSHB, also known as Follitropin subunit beta, is a protein that in humans is encoded by the FSHB gene, and this gene is mapped to 11p14.1. FSHB enables ovarian folliculogenesis to the antral follicle stage and is essential for Sertoli cell proliferation and maintenance of sperm quality in the testis. It can stimulate development of follicle and spermatogenesis in the reproductive organs. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production.

Synonyms: Follicle Stimulating Hormone antibody|Follicle Stimulating Hormone antibody|Follicle stimulating hormone beta polypeptide antibody|Follicle stimulating hormone beta polypeptide antibody|Follicle stimulating hormone beta subunit antibody|Follitropin beta chain antibody|Follitropin beta chain precursor antibody|Follitropin subunit beta antibody|FSH B antibody|FSH-B antibody|FSH-beta antibody|FSHB antibody|FSHbeta antibody

Gene ID: 2488

UniProt: P01225

Pathways: Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process