MICB antibody (N-Term)

Catalog No. ABIN3042366

Product Details anti-MICB Antibody

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Binding Specificity: AA 23-48, N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MICB antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for MHC class I polypeptide-related sequence B(MICB) detection. Tested with WB in Human,Rat.

Sequence: AEPHSLRYNL MVLSQDESVQ SGFLAE

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for MHC class I polypeptide-related sequence B(MICB) detection. Tested with WB in Human,Rat.
Gene Name: MHC class I polypeptide-related sequence B
Protein Name: MHC class I polypeptide-related sequence B

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MICB (23-48aa AEPHSLRYNLMVLSQDESVQSGFLAE).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for MICB

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Alternative Name: MICB (MICB Products)

Synonyms: PERB11.2 antibody, MHC class I polypeptide-related sequence B antibody, MHC class I-related protein-like antibody, MICB antibody, LOC512825 antibody

Background: MHC class I polypeptide-related sequence B is a protein that in humans is encoded by the MICB gene. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Synonyms: MHC class I chain related protein B2 antibody|MHC class I mic B antigen antibody|MHC class I polypeptide related sequence B antibody| MHC class I polypeptide-related sequence B antibody|MIC B antibody|MIC-B antibody|MICB antibody|MICB_HUMAN antibody|PERB11.2 antibody

Gene ID: 4277

UniProt: Q29980

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response