SLC2A12
Reactivity: Human, Mouse, Rat
WB, FACS, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 594
Application Notes
The stated application concentrations are suggested starting points. Titration of the GLUT12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
-20 °C
Storage Comment
After reconstitution, the GLUT12 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Target
GLUT12 (SLC2A12)
(Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 12 (SLC2A12))
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Background
GLUT12, also called Solute carrier family 2, facilitated glucose transporter member 12, is a protein that in humans is encoded by the SLC2A12 gene. It belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion. This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues. By genomic sequence analysis, this gene is mapped to chromosome 6q23.2. GLUT12 was detected in a perinuclear location in MCF7 cells in the absence of insulin, however, it redistributed to the plasma membrane of MCF7 cells grown continuously in the presence of insulin.