SCG3 antibody (C-Term)

Catalog No. ABIN3032526

Product Details anti-SCG3 Antibody

Target: SCG3 (Secretogranin III (SCG3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCG3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Secretogranin 3 (DFINKQADAYVEK) was used as the immunogen for this Secretogranin 3 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Secretogranin 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Secretogranin 3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for SCG3

Target: SCG3 (Secretogranin III (SCG3))

Alternative Name: Secretogranin 3 (SCG3 Products)

Synonyms: SgIII antibody, scg3-A antibody, zgc:73236 antibody, sgiii antibody, DKFZp459J1919 antibody, SGIII antibody, 1B1075 antibody, AI385542 antibody, Chgd antibody, secretogranin III L homeolog antibody, secretogranin III antibody, scg3.L antibody, scg3 antibody, SCG3 antibody, Scg3 antibody

Background: SCG3(secretogranin III) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Genetic variations in the SCG3 gene may influence the risk of obesity through possible regulation of hypothalamic neuropeptide secretion. SCG3 was the only gene within a haplotype block that contained rs3764220. SCG3 mRNA and immunoreactivity were detected in the paraventricular nucleus, lateral hypothalamic area, and arcuate nucleus, and the protein coexisted with orexin, melanin-concentrating hormone, neuropeptide Y, and proopiomelanocortin. SCG3 formed a granule-like structure together with these neuropeptides.

UniProt: Q8WXD2