PIAS4 antibody (C-Term)
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- Target See all PIAS4 Antibodies
- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PIAS4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogen
- An amino acid sequence from the C-terminus of human E3 SUMO-protein ligase PIASg (HPELCKALVKEKLRLD) was used as the immunogen for this PIASg antibody (100% homologous in human, mouse and rat).
- Isotype
- IgG
- Top Product
- Discover our top product PIAS4 Primary Antibody
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- Application Notes
- The stated application concentrations are suggested starting amounts. Titration of the PIASg antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Storage
- -20 °C
- Storage Comment
- After reconstitution, the PIASg antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
- Alternative Name
- PIASg (PIAS4) (PIAS4 Products)
- Synonyms
- PIASY antibody, Piasg antibody, ZMIZ6 antibody, pias4 antibody, piasy antibody, wu:fc54c11 antibody, wu:fi18c10 antibody, wu:fi20e09 antibody, wu:fk93f11 antibody, zgc:66410 antibody, piasg antibody, zmiz6 antibody, LOC100219439 antibody, Pias-gamma antibody, pias4l antibody, wu:fi26h11 antibody, zgc:63923 antibody, protein inhibitor of activated STAT 4 antibody, protein inhibitor of activated STAT, 4 antibody, protein inhibitor of activated STAT, 4a antibody, protein inhibitor of activated STAT 4 L homeolog antibody, protein inhibitor of activated STAT, 4b antibody, PIAS4 antibody, Pias4 antibody, pias4a antibody, pias4.L antibody, pias4 antibody, pias4b antibody
- Background
- Protein inhibitor of activated STAT protein 4 (PIAS4) or Protein inhibitor of activated STAT protein gamma (PIASg or PIASy) is an enzyme that in humans is encoded by the PIAS4 gene. This gene is mapped to 19p13.3. This gene plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. PIASg functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This gene involved in gene silencing.
- UniProt
- Q8N2W9
- Pathways
- JAK-STAT Signaling, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
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