PLK2 antibody (C-Term)

Catalog No. ABIN3032267

Product Details anti-PLK2 Antibody

Target: PLK2 (Polo-Like Kinase 2 (PLK2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Polo-like kinase 2 (SSELKNRMEYALNMLLQRCN) was used as the immunogen for this PLK2 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the PLK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the PLK2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for PLK2

Target: PLK2 (Polo-Like Kinase 2 (PLK2))

Alternative Name: PLK2 (PLK2 Products)

Synonyms: SNK antibody, hPlk2 antibody, hSNK antibody, Snk antibody, PLK2 antibody, Plx2 antibody, MGC53990 antibody, plk2 antibody, zgc:165644 antibody, polo like kinase 2 antibody, polo-like kinase 2 antibody, polo-like kinase 2 L homeolog antibody, polo-like kinase 2b (Drosophila) antibody, Serine/threonine-protein kinase plk-2 antibody, PLK2 antibody, Plk2 antibody, plk2.L antibody, plk2b antibody, plk2 antibody, plk-2 antibody

Background: Polo-like kinase 2, also known as SNK, is an enzyme that in humans is encoded by the PLK2 gene. It is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. The International Radiation Hybrid Mapping Consortium mapped the gene to chromosome 5. Polo-like kinase 2 is involved in synaptic plasticity, centriole duplication and G1/S phase transition. This gene plays a key role in synaptic plasticity and memory by regulating the Ras and Rap protein signalin: required for overactivity-dependent spine remodeling by phosphorylating the Ras activator RASGRF1 and the Rap inhibitor SIPA1L1 leading to their degradation by the proteasome.

UniProt: Q9NYY3