Microtubule Star antibody (N-Term)
MTS
Reactivity: Human, Mouse, Rat
IHC (p), WB
Host: Rabbit
Polyclonal
unconjugated
1 image
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- Target See all Microtubule Star (MTS) products
- Microtubule Star (MTS)
- Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogen
- An amino acid sequence from the N-terminus of human PPP2CA (FTKELDQWIEQLNEC) was used as the immunogen for this PP2Ac antibody (100% homologous in human, mouse and rat).
- Isotype
- IgG
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- Application Notes
- Variations in secondary/substrate sensitivities and test protocols may require the PP2Ac antibody to be titrated for optimal performance.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Storage
- -20 °C
- Storage Comment
- The lyophilized PP2Ac antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.
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- Target
- Microtubule Star (MTS)
- Alternative Name
- PP2Ac
- Synonyms
- AI115466 antibody, D8Ertd766e antibody, PP2Ac antibody, PP2CA antibody, PP2Calpha antibody, RP-C antibody, protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform antibody, protein phosphatase 2 catalytic subunit alpha antibody, Ppp2cb antibody, PPP2CA antibody
- Background
- The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue (Leu309) of PPP2CA is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.
- UniProt
- P67775
- Pathways
- PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
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