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IRAK2 antibody (C-Term)

IRAK2 Reactivity: Human, Mouse, Rat WB, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031491
  • Target See all IRAK2 Antibodies
    IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
    Binding Specificity
    • 15
    • 13
    • 8
    • 8
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 79
    • 11
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 80
    • 3
    Rabbit
    Clonality
    • 72
    • 11
    Polyclonal
    Conjugate
    • 36
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRAK2 antibody is un-conjugated
    Application
    • 53
    • 37
    • 16
    • 14
    • 14
    • 10
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogen
    An amino acid sequence from the C-terminus of human IRAK2 (EAKRKLMENILLYKEEK) was used as the immunogen for this IRAK2 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product IRAK2 Primary Antibody
  • Application Notes
    The stated application concentrations are suggested starting points. Titration of the IRAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the IRAK2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
    Alternative Name
    IRAK2 (IRAK2 Products)
    Synonyms
    IRAK-2 antibody, 6330415L08Rik antibody, AI649099 antibody, interleukin 1 receptor associated kinase 2 antibody, interleukin-1 receptor-associated kinase 2 antibody, IRAK2 antibody, Irak2 antibody
    Background
    Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene. This gene is mapped to 3p25.3. Interleukin-1 receptor-associated kinase 2 is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor(IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. It binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
    UniProt
    O43187
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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