Integrin beta 2 antibody (AA 17-382)
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- Target See all Integrin beta 2 (ITGB2) Antibodies
- Integrin beta 2 (ITGB2)
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Binding Specificity
- AA 17-382
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Integrin beta 2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogen
- Human partial recombinant protein (AA 17-382) was used as the immunogen for this MAC-1 antibody.
- Isotype
- IgG
- Top Product
- Discover our top product ITGB2 Primary Antibody
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anti-Integrin beta 2 (ITGB2) antibody
ITGB2 Reactivity: Human FACS, WB, IP, IHC (fro), IHC (p) Host: Mouse Monoclonal MEM-48 unconjugated
anti-Integrin beta 2 (ITGB2) antibodyITGB2 Reactivity: Human FACS, WB, IP, Func, IHC (fro), IHC (p) Host: Mouse Monoclonal MEM-48 unconjugated
anti-Integrin beta 2 (ITGB2) antibody (Biotin)ITGB2 Reactivity: Human FACS, WB, IP, IHC (fro), IHC (p) Host: Mouse Monoclonal MEM-48 Biotin
anti-Integrin beta 2 (ITGB2) antibody (FITC)ITGB2 Reactivity: Human FACS Host: Mouse Monoclonal MEM-48 FITC
anti-Integrin beta 2 (ITGB2) antibody (PE)ITGB2 Reactivity: Human FACS Host: Mouse Monoclonal MEM-48 PE
anti-Integrin beta 2 (ITGB2) (AA 70-170) antibodyITGB2 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Integrin beta 2 (ITGB2) antibodyITGB2 Reactivity: Mouse FACS, WB, IP, Func, IHC (fro), IHC (p) Host: Rat Monoclonal M18-2 unconjugated
anti-Integrin beta 2 (ITGB2) (AA 559-700) antibodyITGB2 Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 3C11G5 unconjugated
anti-Integrin beta 2 (ITGB2) antibodyITGB2 Reactivity: Mouse FACS, WB, IP, IHC (fro), IHC (p) Host: Rat Monoclonal M18-2 unconjugated
anti-Integrin beta 2 (ITGB2) antibodyITGB2 Reactivity: Human, Cow FACS, IP, ICC Host: Mouse Monoclonal IVA35 unconjugated
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- Application Notes
- The stated application concentrations are suggested starting amounts. Titration of the MAC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Storage
- -20 °C
- Storage Comment
- After reconstitution, the MAC-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- Integrin beta 2 (ITGB2)
- Alternative Name
- MAC-1 (ITGB2 Products)
- Synonyms
- CD18 antibody, LAD antibody, LCAMB antibody, LFA-1 antibody, MAC-1 antibody, MF17 antibody, MFI7 antibody, 2E6 antibody, AI528527 antibody, Cd18 antibody, Lfa1 antibody, ITGB2 antibody, itgb2 antibody, itgb2-a antibody, itgb2-b antibody, integrin subunit beta 2 antibody, integrin beta 2 antibody, integrin subunit beta 2 S homeolog antibody, ITGB2 antibody, Itgb2 antibody, itgb2.S antibody
- Background
- Macrophage-1 alpha (MAC-1) or CD11b are glycoproteins encoded by the ITGAM gene. It is mapped to 16p11.2. MAC-1 has a role in vascular repair after mechanical arterial injury. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Additionally, it likely recognizes the R-G-D peptide in C3b, and it is also a receptor for fibrinogen, factor X and ICAM1.
- Gene ID
- 3684
- Pathways
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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