FAF1 antibody (N-Term)

Catalog No. ABIN3030906

Product Details anti-FAF1 Antibody

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAF1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human FAF1 (MASNMDREMILADFQACTGIEN) was used as the immunogen for this FAF1 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the FAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the FAF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for FAF1

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Alternative Name: FAF1 (FAF1 Products)

Synonyms: faf1 antibody, MGC53741 antibody, MGC80303 antibody, FAF1 antibody, zgc:55752 antibody, wu:fc25h12 antibody, HFAF1s antibody, UBXD12 antibody, UBXN3A antibody, hFAF1 antibody, AA408698 antibody, Dffrx antibody, Fam antibody, Fas (TNFRSF6) associated factor 1 S homeolog antibody, Fas (TNFRSF6) associated factor 1 L homeolog antibody, Fas associated factor 1 antibody, Fas (TNFRSF6) associated factor 1 antibody, Fas-associated factor 1 antibody, faf1.S antibody, faf1.L antibody, FAF1 antibody, faf1 antibody, Faf1 antibody

Background: Fas-associated factor-1(FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 is involved in negative regulation of NF-kappaB activation. In addition to the previously known function as a component of the Fas death-inducing signaling complex, i.e. NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction. hFAF1 was expressed abundantly in testis, skeletal muscle, and heart as 2.8 kb mRNA. Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines.

UniProt: Q9UNN5

Pathways: Maintenance of Protein Location