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Calpain antibody (Catalytic Subunit)

Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030266
  • Target See all Calpain products
    Calpain
    Binding Specificity
    • 2
    • 1
    • 1
    AA 396-555, Catalytic Subunit
    Reactivity
    Human, Mouse, Rat
    Host
    • 4
    • 3
    Rabbit
    Clonality
    • 4
    • 3
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    This Calpain antibody is un-conjugated
    Application
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogen
    Human recombinant protein from the CAPN1 catalytic subunit (AA 396-555) was used as the immunogen for this Calpain antibody.
    Isotype
    IgG
  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the Calpain antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the Calpain antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    Calpain
    Abstract
    Calpain Products
    Synonyms
    CG18152 antibody, CG7563 antibody, Dmel\\CG7563 antibody, EST C antibody, calpain antibody, Tb08.28A12.350 antibody, Calpain-A antibody, hypothetical protein antibody, calpain 11 antibody, calpain antibody, CalpA antibody, T11A5.6 antibody, CAPN11 antibody, Tb927.8.8330 antibody
    Background
    Calpain 1 is also known as CAPN, CAPN1 and muCL. The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. The CPN1 gene encodes the catalytic subunit of the ubiquitous enzyme, Calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
    Gene ID
    823
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