BNIP3L/NIX antibody (AA 122-152)

Catalog No. ABIN3030152

Product Details anti-BNIP3L/NIX Antibody

Target: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Binding Specificity: AA 122-152

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BNIP3L/NIX antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Purified

Immunogen: A portion of amino acids 122-152 from the human protein (BH3 domain) was used as the immunogen for this BNIP3L antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the BNIP3L antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the BNIP3L antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for BNIP3L/NIX

Target: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Alternative Name: BNIP3L (BNIP3L Products)

Background: BNIP3L is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. The protein encoded by this gene is a functional homolog of BNIP3, a proapoptotic protein. This protein may function simultaneously with BNIP3 and may play a role in tumor suppression.

UniProt: O60238

Pathways: Autophagy