Apelin antibody (C-Term)
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- Target See all Apelin (APLN) Antibodies
- Apelin (APLN)
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Apelin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogen
- An amino acid sequence from the C-terminus of Apelin (RKFRRQRPRLSHKGPMPF) was used as the immunogen for this Apelin antibody (100% homologous in human, mouse and rat).
- Isotype
- IgG
- Top Product
- Discover our top product APLN Primary Antibody
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- Application Notes
- The stated application concentrations are suggested starting amounts. Titration of the Apelin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Storage
- -20 °C
- Storage Comment
- After reconstitution, the Apelin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- Apelin (APLN)
- Alternative Name
- Apelin (APLN Products)
- Synonyms
- APLN antibody, Xapelin antibody, xnpep2 antibody, preproapelin antibody, 6030430G11Rik antibody, Apel antibody, APEL antibody, XNPEP2 antibody, apelin antibody, apelin S homeolog antibody, apln antibody, APLN antibody, apln.S antibody, Apln antibody
- Background
- Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei that acts on specific receptors located on vasopressinergic neurons. The gene is at Xq25-q26.3, based on sequence similarity between the Apelin sequence and a chromosome X PAC clone. This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.
- UniProt
- Q9ULZ1
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour
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