CHRM1 antibody (AA 303-317)

Catalog No. ABIN3029680

Product Details anti-CHRM1 Antibody

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Binding Specificity: AA 303-317

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Amino acids 303-317 (KMPMVDPEAQAPTKQ-human) were used as the immunogen for this muscarinic AChR antibody (100% mouse homology).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the AChR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the AChR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for CHRM1

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Alternative Name: AChR (Muscarinic) (CHRM1 Products)

Synonyms: M1 antibody, CHRM1 antibody, HM1 antibody, M1R antibody, mAChR antibody, Chrm-1 antibody, cholinergic receptor muscarinic 1 antibody, cholinergic receptor, muscarinic 1 antibody, cholinergic receptor, muscarinic 1, CNS antibody, CHRM1 antibody, Chrm1 antibody

Background: Muscarinic acetylcholine receptor 1 is a muscarinic receptor. The muscarinic cholinergic receptors belong to a larger family of GPCRs. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. AChR is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract.

UniProt: P11229

Pathways: Synaptic Membrane