SLC2A10
Reactivity: Rat
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 350
Application Notes
ELISA. Western Blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 5 μg/mL. This GLUT10 antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS, 0.02 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target
SLC2A10
(Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 10 (SLC2A10))
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Background
Non-insulin-dependent diabetes mellitus (NIDDM) is a multifactoral disease with both environmental and genetics causes. Genone-wide screening procedures have identified several susceptibility loci for NIDDM within the human genome. A putative sugar transporter has been localized to human chromosome 20q12- q13.1, one of the genomic loci associated with NIDDM. Because of the strong resemblance of this novel protein to members of the mammalian facilitative glucose transporter family (GLUT), the protein is known as GLUT10 (HGMW-approved gene symbol SLC2A10). Data suggests that GLUT10 is an excellent candidate for a susceptibility gene involved in NIDDM.Synonyms: GLUT-10, Glucose transporter 10, Glucose transporter type 10, Solute carrier family 2 facilitated glucose transporter member 10