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TICAM2 antibody (C-Term)

TICAM2 Reactivity: Human, Mouse, Rat WB, ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3029187
  • Target See all TICAM2 Antibodies
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Binding Specificity
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 49
    • 16
    • 14
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 47
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 51
    Polyclonal
    Conjugate
    • 29
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TICAM2 antibody is un-conjugated
    Application
    • 43
    • 24
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Antigen affinity
    Immunogen
    An amino acid sequence from the C-terminus of human Translocating chain-associating membrane protein 1 (KFINFQLRRWREHSAFQA) was used as the immunogen for this TRAM antibody (100% homologous in human, mouse and rat).
    Isotype
    IgG
  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the TRAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the TRAM antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Alternative Name
    TRAM (TICAM2 Products)
    Synonyms
    MyD88-4 antibody, TICAM-2 antibody, TIRAP3 antibody, TIRP antibody, TRAM antibody, B430113A10 antibody, Tirp antibody, Trif antibody, toll like receptor adaptor molecule 2 antibody, toll-like receptor adaptor molecule 2 antibody, TICAM2 antibody, Ticam2 antibody
    Background
    By crosslinking and reconstitution of canine proteoliposomes, followed by microsequencing and PCR screening of canine kidney and HeLa cell cDNA libraries, Gorlich et al.(1992) isolated cDNAs encoding TRAM (translocating chain-associating membrane protein). The International Radiation Hybrid Mapping Consortium mapped the gene to chromosome 8. Sequence analysis predicted that human TRAM is a 374-amino acid, 8-pass transmembrane protein that shares 95 % amino acid identity with the canine protein. Functional analysis indicated that the protein influences glycosylation and is stimulatory or required for the translocation of secretory proteins.
    UniProt
    Q15629
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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