Angiostatin antibody (AA 103-352)

Catalog No. ABIN3028464

Product Details anti-Angiostatin Antibody

Target: Angiostatin (ANG)

Binding Specificity: AA 103-352

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiostatin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 103-352) was used as the immunogen for this Angiostatin K1-3 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Angiostatin K1-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Angiostatin K1-3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Angiostatin

Target: Angiostatin (ANG)

Alternative Name: Angiostatin K1-3 (ANG Products)

Synonyms: ALS9 antibody, HEL168 antibody, RNASE4 antibody, RNASE5 antibody, LPA antibody, AI649309 antibody, Pg antibody, Ab1-346 antibody, AI385586 antibody, Ang1 antibody, Rnase5 antibody, Rnase5a antibody, angiogenin antibody, plasminogen antibody, angiogenin, ribonuclease, RNase A family, 5 antibody, ANG antibody, PLG antibody, Plg antibody, Ang antibody

Background: Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity(ED50=70nM) relative to kringles 1-4(ED50 = 135nM).

UniProt: P00747

Pathways: Lipid Metabolism