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SPIB antibody (C-Term)
SPIB
Reactivity: Human, Mouse
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SPIB Antibody
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Target
See all SPIB Antibodies
SPIB
(Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
Binding Specificity
All epitopes for SPIB antibodies
C-Term
Reactivity
All reactivities for SPIB antibodies
Human, Mouse
Host
All hosts for SPIB antibodies
Rabbit
Clonality
All clonalities for SPIB antibodies
Polyclonal
Conjugate
All conjugates for SPIB antibodies
This SPIB antibody is un-conjugated
Application
All applications for SPIB antibodies
Western Blotting (WB)
Purification
Protein A affinity chromatography
Immunogen
A recombinant protein fragment from the C-terminal half of SPIB was used as the immunogen for this antibody.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.\. Western blot: 4-8 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target Details for SPIB
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Target
SPIB
(Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
Alternative Name
SPIB (SPIB Products )
Synonyms
spi-b antibody, spib antibody, spiba antibody, SPI-B antibody, B42b-like antibody, Spi-B antibody, Spi-B transcription factor L homeolog antibody, Spi-B transcription factor antibody, Spi-B transcription factor (Spi-1/PU.1 related) antibody, spib.L antibody, SPIB antibody, Spib antibody
Background
SPIB is a transcription factor in the Ets family. It is found in lymphoid cells and not in monocytes or myeloid cells. SPIB is a regulator of pDC development via its interaction with ID2, E2-2 and BCL2-A1. It promotes E2-2 activity and suppresses Id2 expression to enhance pDC development. It also promotes pDC survival by activation of the antiapoptotic gene BCL2-A1.
Gene ID
6689
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