UNC93B1 antibody (C-Term)
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- Target See all UNC93B1 Antibodies
- UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UNC93B1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Protein A Affinity Chromatography
- Immunogen
- A recombinant protein fragment from the C-terminal portion of UNC93B was used as the immunogen for this antibody.
- Isotype
- IgG
- Top Product
- Discover our top product UNC93B1 Primary Antibody
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- Application Notes
- Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.\. Western blot: 3-6 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the antibody and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles.
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- Target
- UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
- Alternative Name
- UNC93B (UNC93B1 Products)
- Synonyms
- UNC93 antibody, IIAE1 antibody, UNC93B antibody, Unc-93B1 antibody, Unc93b antibody, unc-93 homolog B1, TLR signaling regulator antibody, unc-93 homolog B1 (C. elegans) antibody, UNC93B1 antibody, Unc93b1 antibody
- Background
- UNC93B is part of the innate immune response via its direct interaction with the intracellular toll-like receptors TLR3, 7, and 9. UNC93B aids in the trafficing of these TLRs from the ER to the endolysosomes, where they bind ligands and initiate immune response. In the absence of UNC93B, these TLRs are unable to respond to foreign stimuli.
- Gene ID
- 81622
- Pathways
- TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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