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ZAP70 antibody (pTyr319)

ZAP70 Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3023646
  • Target See all ZAP70 Antibodies
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    Binding Specificity
    • 34
    • 32
    • 25
    • 20
    • 17
    • 16
    • 14
    • 10
    • 10
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr319
    Reactivity
    • 269
    • 126
    • 48
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    Human
    Host
    • 204
    • 61
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 197
    • 72
    Polyclonal
    Conjugate
    • 133
    • 16
    • 15
    • 12
    • 11
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This ZAP70 antibody is un-conjugated
    Application
    • 192
    • 117
    • 102
    • 64
    • 53
    • 53
    • 43
    • 23
    • 22
    • 21
    • 13
    • 12
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Sequence
    SPYSD
    Cross-Reactivity
    Human
    Characteristics
    Phosphorylated Antibodies
    Immunogen
    A synthetic phosphorylated peptide around Y319 of human ZAP70 (NP_001070.2).
    Isotype
    IgG
    Top Product
    Discover our top product ZAP70 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    Alternative Name
    ZAP70 (ZAP70 Products)
    Synonyms
    SRK antibody, STCD antibody, STD antibody, TZK antibody, ZAP-70 antibody, 70kDa antibody, AI327364 antibody, Srk antibody, mrtle antibody, mur antibody, zap70 antibody, MGC80670 antibody, MGC88962 antibody, ZAP70 antibody, zgc:110383 antibody, zeta chain of T-cell receptor associated protein kinase 70 antibody, putative tyrosine-protein kinase zap-70 antibody, zeta-chain (TCR) associated protein kinase antibody, zeta chain of T cell receptor associated protein kinase 70 antibody, zeta-chain (TCR) associated protein kinase 70kDa antibody, zeta chain of T cell receptor associated protein kinase 70kDa L homeolog antibody, zeta chain of T cell receptor associated protein kinase 70kDa antibody, tyrosine-protein kinase ZAP-70 antibody, ZAP70 antibody, Smp_149470 antibody, Zap70 antibody, zap70.L antibody, zap70 antibody, LOC707555 antibody, LOC100342021 antibody, LOC100390922 antibody, LOC100542877 antibody
    Background
    This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.,ZAP70,ADMIO2,IMD48,SRK,STCD,STD,TZK,ZAP-70,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Protein phosphorylation,ZAP70
    Molecular Weight
    35 kDa/55 kDa/69 kDa
    Gene ID
    7535
    UniProt
    P43403
    Pathways
    TCR Signaling, Ubiquitin Proteasome Pathway
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