ALDH4A1 antibody (AA 354-563)

Catalog No. ABIN3023403

Product Details anti-ALDH4A1 Antibody

Target: ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))

Binding Specificity: AA 354-563

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH4A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: LYVPHSLWPQ IKGRLLEEHS RIKVGDPAED FGTFFSAVID AKSFARIKKW LEHARSSPSL TILAGGKCDD SVGYFVEPCI VESKDPQEPI MKEEIFGPVL SVYVYPDDKY KETLQLVDST TSYGLTGAVF SQDKDVVQEA TKVLRNAAGN FYINDKSTGS IVGQQPFGGA RASGTNDKPG GPHYILRWTS PQVIKETHKP LGDWSYAYMQ

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 354-563 of human ALDH4A1 (NP_003739.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ALDH4A1

Target: ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))

Alternative Name: ALDH4A1 (ALDH4A1 Products)

Background: This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.,ALDH4A1,ALDH4,P5CD,P5CDh,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,ALDH4A1

Molecular Weight: 55 kDa/56 kDa/61 kDa

Gene ID: 8659

UniProt: P30038

Pathways: Monocarboxylic Acid Catabolic Process