USP7 antibody (AA 206-1102)

Catalog No. ABIN3023238

Product Details anti-USP7 Antibody

Target: USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))

Binding Specificity: AA 206-1102

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DSKKHTGYVG LKNQGATCYM NSLLQTLFFT NQLRKAVYMM PTEGDDSSKS VPLALQRVFY ELQHSDKPVG TKKLTKSFGW ETLDSFMQHD VQELCRVLLD NVENKMKGTC VEGTIPKLFR GKMVSYIQCK EVDYRSDRRE DYYDIQLSIK GKKNIFESFV DYVAVEQLDG DNKYDAGEHG LQEAEKGVKF LTLPPVLHLQ LMRFMYDPQT DQNIKINDRF EFPEQLPLDE FLQKTDPKDP ANYILHAVLV HSGDNHGGHY VVYLNPKGDG KWCKFDDDVV SRCTKEEAIE HNYGGHDDDL SVRHCTNAYM LVYIRESKLS EVLQAVTDHD IPQQLVERLQ EEKRIEAQKR KERQEAHLYM QVQIVAEDQF CGHQGNDMYD EEKVKYTVFK VLKNSSLAEF VQSLSQTMGF PQDQIRLWPM QARSNGTKRP AMLDNEADGN KTMIELSDNE NPWTIFLETV DPELAASGAT LPKFDKDHDV MLFLKMYDPK TRSLNYCGHI YTPISCKIRD LLPVMCDRAG FIQDTSLILY EEVKPNLTER IQDYDVSLDK ALDELMDGDI IVFQKDDPEN DNSELPTAKE YFRDLYHRVD VIFCDKTIPN DPGFVVTLSN RMNYFQVAKT VAQRLNTDPM LLQFFKSQGY RDGPGNPLRH NYEGTLRDLL QFFKPRQPKK LYYQQLKMKI TDFENRRSFK CIWLNSQFRE EEITLYPDKH GCVRDLLEEC KKAVELGEKA SGKLRLLEIV SYKIIGVHQE DELLECLSPA TSRTFRIEEI PLDQVDIDKE NEMLVTVAHF HKEVFGTFGI PFLLRIHQGE HFREVMKRIQ SLLDIQEKEF EKFKFAIVMM GRHQYINEDE YEVNLKDFEP QPGNMSHPRP WLGLDHFNKA PKRSRYTYLE KAIKIHN

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 206-1102 of human USP7/HAUSP (NP_003461.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for USP7

Target: USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))

Alternative Name: USP7 (USP7 Products)

Synonyms: CG1490 antibody, Dmel\\CG1490 antibody, USP7 antibody, 2210010O09Rik antibody, AA409944 antibody, AA617399 antibody, AU019296 antibody, AW548146 antibody, C80752 antibody, Hausp antibody, HAUSP antibody, TEF1 antibody, UBP antibody, Ubiquitin-specific protease 7 antibody, ubiquitin carboxyl-terminal hydrolase 7 antibody, ubiquitin specific peptidase 7 antibody, Usp7 antibody, LOC100201254 antibody, USP7 antibody

Background: The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.,USP7,HAUSP,TEF1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Ubiquitin,USP7

Molecular Weight: 126 kDa/128 kDa

Gene ID: 7874

UniProt: Q93009