UHRF2 antibody (AA 76-359)

Catalog No. ABIN3023235

The Rabbit Polyclonal anti-UHRF2 antibody has been validated for WB. It is suitable to detect UHRF2 in samples from Mouse.

Quick Overview for UHRF2 antibody (AA 76-359) (ABIN3023235)

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UHRF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UHRF2 Antibody

Binding Specificity: AA 76-359

Sequence: DSSLPSTSKQ NDAQVKPSSH NPPKVKKTAR GGSSSQPSTS ARTCLIDPGF GLYKVNELVD ARDVGLGAWF EAHIHSVTRA SDGHSRGKTP LKNGSSYKRT NGNVNHNSKE NTNKLDNVPS TSNSDSVAAD EDVIYHIEYD EYPESGILEM NVKDLRPRAR TILKWNELNV GDVVMVNYNV ENPGKRGFWY DAEITTLKTI SRTKKEVRVK VFLGGSEGTL NDCRVMSVDE IFKIEKPGAH PISFADGKFL RKNDPECDLC GGDPDKTCHM CSCHKCGEKR DPNM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 76-359 of mouse Uhrf2 (NP_659122.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UHRF2

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Alternative Name: UHRF2

Background: This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.,UHRF2,NIRF,RNF107,TDRD23,URF2,Uhrf2,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,Ubiquitin,UHRF2

Molecular Weight: 56 kDa/89 kDa

Gene ID: 109113

UniProt: Q7TMI3