PPP2R2A antibody (AA 1-447)

Catalog No. ABIN3023154

Product Details anti-PPP2R2A Antibody

Target: PPP2R2A (Protein Phosphatase 2 Regulatory Subunit 2A (PPP2R2A))

Binding Specificity: AA 1-447

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MAGAGGGNDI QWCFSQVKGA VDDDVAEADI ISTVEFNHSG ELLATGDKGG RVVIFQQEQE NKIQSHSRGE YNVYSTFQSH EPEFDYLKSL EIEEKINKIR WLPQKNAAQF LLSTNDKTIK LWKISERDKR PEGYNLKEED GRYRDPTTVT TLRVPVFRPM DLMVEASPRR IFANAHTYHI NSISINSDYE TYLSADDLRI NLWHLEITDR SFNIVDIKPA NMEELTEVIT AAEFHPNSCN TFVYSSSKGT IRLCDMRASA LCDRHSKLFE EPEDPSNRSF FSEIISSISD VKFSHSGRYM MTRDYLSVKI WDLNMENRPV ETYQVHEYLR SKLCSLYEND CIFDKFECCW NGSDSVVMTG SYNNFFRMFD RNTKRDITLE ASRENNKPRT VLKPRKVCAS GKRKKDEISV DSLDFNKKIL HTAWHPKENI IAVATTNNLY IFQDKVN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-447 of human PP2A-B55alpha/PR55alpha/PPP2R2A (NP_002708.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPP2R2A

Target: PPP2R2A (Protein Phosphatase 2 Regulatory Subunit 2A (PPP2R2A))

Alternative Name: PPP2R2A (PPP2R2A Products)

Synonyms: B55A antibody, B55ALPHA antibody, PR52A antibody, PR55A antibody, 2410004D02Rik antibody, mKIAA1541 antibody, PPP2R2A antibody, protein phosphatase 2 regulatory subunit Balpha antibody, protein phosphatase 2, regulatory subunit B, alpha antibody, PPP2R2A antibody, Ppp2r2a antibody

Background: The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described.,PPP2R2A,B55A,B55ALPHA,PR52A,PR55A,PR55alpha,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centromere,Wnt/β-Catenin Signaling Pathway,Neuroscience,PPP2R2A

Molecular Weight: 51 kDa/53 kDa

Gene ID: 5520

UniProt: P63151

Pathways: Mitotic G1-G1/S Phases, Hepatitis C