PDGFRB antibody (AA 887-1106)

Catalog No. ABIN3023139

Product Details anti-PDGFRB Antibody

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Binding Specificity: AA 887-1106

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: WSFGILLWEI FTLGGTPYPE LPMNEQFYNA IKRGYRMAQP AHASDEIYEI MQKCWEEKFE IRPPFSQLVL LLERLLGEGY KKKYQQVDEE FLRSDHPAIL RSQARLPGFH GLRSPLDTSS VLYTAVQPNE GDNDYIIPLP DPKPEVADEG PLEGSPSLAS STLNEVNTSS TISCDSPLEP QDEPEPEPQL ELQVEPEPEL EQLPDSGCPA PRAEAEDSFL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 887-1106 of human PDGFRB (NP_002600.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDGFRB

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Alternative Name: PDGFRB (PDGFRB Products)

Synonyms: AI528809 antibody, CD140b antibody, PDGFR-1 antibody, Pdgfr antibody, CD140B antibody, IBGC4 antibody, JTK12 antibody, PDGFR antibody, PDGFR1 antibody, platelet derived growth factor receptor, beta polypeptide antibody, platelet derived growth factor receptor beta antibody, Pdgfrb antibody, PDGFRB antibody

Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.,CD140B,IBGC4,IMF1,JTK12,KOGS,PDGFR,PDGFR-1,PDGFR1,PENTT,PDGF Receptor beta,PDGFRB,PDGFR beta,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,CD markers,Cardiovascular,Angiogenesis,PDGFRB

Molecular Weight: 37 kDa/123 kDa

Gene ID: 5159

UniProt: P09619

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling