NDRG1 antibody (AA 175-394)

Catalog No. ABIN3023026

Product Details anti-NDRG1 Antibody

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Binding Specificity: AA 175-394

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDRG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: WAASKISGWT QALPDMVVSH LFGKEEMQSN VEVVHTYRQH IVNDMNPGNL HLFINAYNSR RDLEIERPMP GTHTVTLQCP ALLVVGDSSP AVDAVVECNS KLDPTKTTLL KMADCGGLPQ ISQPAKLAEA FKYFVQGMGY MPSASMTRLM RSRTASGSSV TSLDGTRSRS HTSEGTRSRS HTSEGTRSRS HTSEGAHLDI TPNSGAAGNS AGPKSMEVSC

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 175-394 of human NDRG1 (NP_001128714.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NDRG1

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Alternative Name: NDRG1 (NDRG1 Products)

Background: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,NDRG1,CAP43,CMT4D,DRG-1,DRG1,GC4,HMSNL,NDR1,NMSL,PROXY1,RIT42,RTP,TARG1,TDD5,Epigenetics & Nuclear Signaling,Cancer,Invasion and Metastasis,Signal Transduction,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis,NDRG1

Molecular Weight: 33 kDa/35 kDa/42 kDa

Gene ID: 10397

UniProt: Q92597