Thrombospondin 1 antibody (AA 80-360)

Catalog No. ABIN3022979

Product Details anti-Thrombospondin 1 Antibody

Target: Thrombospondin 1 (THBS1)

Binding Specificity: AA 80-360

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thrombospondin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DAVRAEKGFL LLASLRQMKK TRGTLLALER KDHSGQVFSV VSNGKAGTLD LSLTVQGKQH VVSVEEALLA TGQWKSITLF VQEDRAQLYI DCEKMENAEL DVPIQSVFTR DLASIARLRI AKGGVNDNFQ GVLQNVRFVF GTTPEDILRN KGCSSSTSVL LTLDNNVVNG SSPAIRTNYI GHKTKDLQAI CGISCDELSS MVLELRGLRT IVTTLQDSIR KVTEENKELA NELRRPPLCY HNGVQYRNNE EWTVDSCTEC HCQNSVTICK KVSCPIMPCS N

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-360 of human THBS1 (NP_003237.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Thrombospondin 1 antibody (ABIN3022979)

Shen, Cao, Wang, Ma, Zeng, Liu, Li, Tao, Gong, Xie: "Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 175, (2018) (PubMed).

Target Details for Thrombospondin 1

Target: Thrombospondin 1 (THBS1)

Alternative Name: THBS1 (THBS1 Products)

Synonyms: THBS antibody, THBS-1 antibody, TSP antibody, TSP-1 antibody, TSP1 antibody, Thbs-1 antibody, tbsp1 antibody, thrombospondin-1 antibody, thbs antibody, thbs-1 antibody, tsp antibody, tsp-1 antibody, tsp1 antibody, Tsp1 antibody, THBS1 antibody, Tsp-1 antibody, wu:fc48c03 antibody, si:dkey-11e23.1 antibody, tsp2 antibody, thrombospondin 1 antibody, thrombospondin 1 S homeolog antibody, thrombospondin 1b antibody, thrombospondin 2 L homeolog antibody, THBS1 antibody, Thbs1 antibody, thbs1.S antibody, thbs1b antibody, thbs1 antibody, thbs2.L antibody

Background: The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.,THBS1,THBS,THBS-1,TSP,TSP-1,TSP1,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Cell Adhesion,Endocrine & Metabolism,Neuroscience,Cell Type Marker,Stem Cells,Cardiovascular,Angiogenesis,Angiogenic inhibitory factors,Blood,Hypoxia,Astrocyte marker,THBS1

Molecular Weight: 120 kDa/129 kDa

Gene ID: 7057

UniProt: P07996

Pathways: Autophagy