EXT1 antibody (AA 467-746)

Catalog No. ABIN3022737

Product Details anti-EXT1 Antibody

Target: EXT1 (Exostosin 1 (EXT1))

Binding Specificity: AA 467-746

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: YYYANLGLKP PSKFTAVIHA VTPLVSQSQP VLKLLVAAAK SQYCAQIIVL WNCDKPLPAK HRWPATAVPV VVIEGESKVM SSRFLPYDNI ITDAVLSLDE DTVLSTTEVD FAFTVWQSFP ERIVGYPARS HFWDNSKERW GYTSKWTNDY SMVLTGAAIY HKYYHYLYSH YLPASLKNMV DQLANCEDIL MNFLVSAVTK LPPIKVTQKK QYKETMMGQT SRASRWADPD HFAQRQSCMN TFASWFGYMP LIHSQMRLDP VLFKDQVSIL RKKYRDIERL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 467-746 of human EXT1 (NP_000118.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:10 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EXT1

Target: EXT1 (Exostosin 1 (EXT1))

Alternative Name: EXT1 (EXT1 Products)

Background: This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses.,EXT1,EXT,LGCR,LGS,TRPS2,TTV,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,EXT1

Molecular Weight: 86 kDa

Gene ID: 2131

UniProt: Q16394

Pathways: Glycosaminoglycan Metabolic Process