Phospholipase C beta 1 antibody (AA 917-1216)

Catalog No. ABIN3022699

Product Details anti-Phospholipase C beta 1 Antibody

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Binding Specificity: AA 917-1216

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C beta 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KSFVKLQKKH YKEMKDLVKR HHKKTTDLIK EHTTKYNEIQ NDYLRRRAAL EKSAKKDSKK KSEPSSPDHG SSTIEQDLAA LDAEMTQKLI DLKDKQQQQL LNLRQEQYYS EKYQKREHIK LLIQKLTDVA EECQNNQLKK LKEICEKEKK ELKKKMDKKR QEKITEAKSK DKSQMEEEKT EMIRSYIQEV VQYIKRLEEA QSKRQEKLVE KHKEIRQQIL DEKPKLQVEL EQEYQDKFKR LPLEILEFVQ EAMKGKISED SNHGSAPLSL SSDPGKVNHK TPSSEELGGD IPGKEFDTPL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 917-1216 of human PLCB1 (NP_056007.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Phospholipase C beta 1

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Alternative Name: PLCB1 (PLCB1 Products)

Synonyms: PLCB1 antibody, 3110043I21Rik antibody, AI132408 antibody, Plcb antibody, mKIAA0581 antibody, EIEE12 antibody, PI-PLC antibody, PLC-154 antibody, PLC-I antibody, PLC154 antibody, PLCB1A antibody, PLCB1B antibody, PLC'1 antibody, PLCbeta1 antibody, Phosphb antibody, RATPHOSPHB antibody, phospholipase C beta 1 antibody, phospholipase C beta 1 S homeolog antibody, phospholipase C, beta 1 antibody, PLCB1 antibody, plcb1.S antibody, Plcb1 antibody

Background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.,PLCB1,EIEE12,PI-PLC,PLC-154,PLC-I,PLC-beta-1,PLC154,PLCB1A,PLCB1B,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Neuroscience,Neurodegenerative Diseases,PLCB1

Molecular Weight: 133 kDa/138 kDa

Gene ID: 23236

UniProt: Q9NQ66

Pathways: WNT Signaling, AMPK Signaling, Thyroid Hormone Synthesis, Inositol Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, G-protein mediated Events