SDC2
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:100
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Rickelt, Hynes: "Antibodies and methods for immunohistochemistry of extracellular matrix proteins." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 71-72, pp. 10-27, (2018) (PubMed).
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.,SDC2,CD362,HSPG,HSPG1,SYND2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Growth factor,VEGF,Immunology & Inflammation,CD markers,Neuroscience,Cardiovascular,Angiogenesis,SDC2