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ALDH1A1 antibody (AA 48-147)
ALDH1A1
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ALDH1A1 Antibody
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Target
See all ALDH1A1 Antibodies
ALDH1A1
(Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
Binding Specificity
All epitopes for ALDH1A1 antibodies
AA 48-147
Reactivity
All reactivities for ALDH1A1 antibodies
Human
Host
All hosts for ALDH1A1 antibodies
Rabbit
Clonality
All clonalities for ALDH1A1 antibodies
Polyclonal
Conjugate
All conjugates for ALDH1A1 antibodies
This ALDH1A1 antibody is un-conjugated
Application
All applications for ALDH1A1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Sequence
ELCQVEEGDK EDVDKAVKAA RQAFQIGSPW RTMDASERGR LLYKLADLIE RDRLLLATME SMNGGKLYSN AYLNDLAGCI KTLRYCAGWA DKIQGRTIPI
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 48-147 of human ALDH1A1 (NP_000680.2).
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
References for anti-ALDH1A1 antibody (ABIN3022573)
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Yan, Li, Peng, Long, Fan, Wang, Shi, Xie, Zhao, Yan : "The Fatty Acid β-Oxidation Pathway is Activated by Leucine Deprivation in HepG2 Cells: A Comparative Proteomics Study. " in: Scientific reports , Vol. 7 , Issue 1 , pp. 1914 , (2018 ) (PubMed ).
Yan, Lestari, Long, Fan, Wang, Guo, Yu, Hu, Yang, Chen, Liu, Li, Purnomoadi, Achmadi, Yan : "Comparative Proteomics Analysis Reveals L-Arginine Activates Ethanol Degradation Pathways in HepG2 Cells. " in: Scientific reports , Vol. 6 , pp. 23340 , (2017 ) (PubMed ).
Long, Muhamad, Yan, Yu, Fan, Wang, Li, Purnomoadi, Achmadi, Yan : "Quantitative proteomics analysis reveals glutamine deprivation activates fatty acid β-oxidation pathway in HepG2 cells. " in: Amino acids , Vol. 48 , Issue 5 , pp. 1297-307 , (2017 ) (PubMed ).
Target Details for ALDH1A1
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Target
ALDH1A1
(Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
Alternative Name
ALDH1A1 (ALDH1A1 Products )
Synonyms
ALDC antibody, ALDH-E1 antibody, ALDH1 antibody, ALDH11 antibody, PUMB1 antibody, RALDH1 antibody, AL1A1 antibody, aldc antibody, aldh-e1 antibody, aldh1 antibody, aldh11 antibody, pumb1 antibody, raldh1 antibody, GGADHR antibody, ALDH1A1 antibody, ALDDH antibody, Ahd2 antibody, Aldh1 antibody, Aldh2 antibody, Ahd-2 antibody, Aldh1a2 antibody, E1 antibody, Raldh1 antibody, Aldh1a1 antibody, ALHDII antibody, RALDH 1 antibody, RalDH1 antibody, aldehyde dehydrogenase 1 family member A1 antibody, aldehyde dehydrogenase 1 family, member A1 antibody, aldehyde dehydrogenase 1 family member A1 L homeolog antibody, aldehyde dehydrogenase family 1, subfamily A1 antibody, aldehyde dehydrogenase antibody, retinal dehydrogenase 1 antibody, ALDH1A1 antibody, aldh1a1 antibody, Aldh1a1 antibody, aldh1a1.L antibody, aldH1 antibody, LOC100732581 antibody, LOC101822890 antibody
Background
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.,ALDH1A1,ALDC,ALDH-E1,ALDH1,ALDH11,HEL-9,HEL-S-53e,HEL12,PUMB1,RALDH1,Cancer,Tumor biomarkers,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Stem Cells,Hematopoietic Progenitors,Neuron marker,ALDH1A1
Molecular Weight
54 kDa
Gene ID
216
UniProt
P00352
Pathways
Dopaminergic Neurogenesis
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