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KNG1 antibody (AA 148-427)

KNG1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3022364
  • Target See all KNG1 Antibodies
    KNG1 (Kininogen 1 (KNG1))
    Binding Specificity
    • 10
    • 7
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 148-427
    Reactivity
    • 59
    • 12
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 62
    • 9
    • 4
    Rabbit
    Clonality
    • 68
    • 7
    Polyclonal
    Conjugate
    • 48
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KNG1 antibody is un-conjugated
    Application
    • 53
    • 37
    • 31
    • 11
    • 8
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    PISTQSPDLE PILRHGIQYF NNNTQHSSLF MLNEVKRAQR QVVAGLNFRI TYSIVQTNCS KENFLFLTPD CKSLWNGDTG ECTDNAYIDI QLRIASFSQN CDIYPGKDFV QPPTKICVGC PRDIPTNSPE LEETLTHTIT KLNAENNATF YFKIDNVKKA RVQVVAGKKY FIDFVARETT CSKESNEELT ESCETKKLGQ SLDCNAEVYV VPWEKKIYPT VNCQPLGMIS LMKRPPGFSP FRSSRIGEIK EETTSHLRSC EYKGRPPKAG AEPASEREVS
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 148-427 of human Kininogen 1 (Kininogen 1 (KNG1)) (NP_000884.1).
    Isotype
    IgG
    Top Product
    Discover our top product KNG1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KNG1 (Kininogen 1 (KNG1))
    Alternative Name
    KNG1 (KNG1 Products)
    Synonyms
    BDK antibody, BK antibody, KNG antibody, Kng antibody, KNG2 antibody, fb64g01 antibody, wu:fb64g01 antibody, zgc:103569 antibody, kininogen antibody, bdk antibody, kng antibody, KNG1 antibody, IHRP antibody, KINKG antibody, KINKH antibody, Kng1 antibody, Kngk antibody, kininogen 1 antibody, kininogen 1 L homeolog antibody, inter-alpha-trypsin inhibitor heavy chain family member 4 antibody, kininogen 2-like 1 antibody, KNG1 antibody, Kng1 antibody, kng1 antibody, kng1.L antibody, ITIH4 antibody, Kng2l1 antibody
    Background
    This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.,KNG1,BDK,BK,KNG,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Cardiovascular,Blood,KNG1
    Molecular Weight
    43 kDa/47 kDa/71 kDa
    Gene ID
    3827
    UniProt
    P01042
    Pathways
    ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
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