SELPLG antibody (AA 40-280)

Catalog No. ABIN3022340

Product Details anti-SELPLG Antibody

Target: SELPLG (Selectin P Ligand (SELPLG))

Binding Specificity: AA 40-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SELPLG antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RRQATEYEYL DYDFLPETEP PEMLRNSTDT TPLTGPGTPE STTVEPAARR STGLDAGGAV TELTTELANM GNLSTDSAAM EIQTTQPAAT EAQTTPLAAT EAQTTRLTAT EAQTTPLAAT EAQTTPPAAT EAQTTQPTGL EAQTTAPAAM EAQTTAPAAM EAQTTPPAAM EAQTTQTTAM EAQTTAPEAT EAQTTQPTAT EAQTTPLAAM EALSTEPSAT EALSMEPTTK RGLFIPFSVS S

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-280 of human SELPLG (NP_002997.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Alternative Name: SELPLG (SELPLG Products)

Synonyms: CD162 antibody, CLA antibody, PSGL-1 antibody, PSGL1 antibody, SELPLG antibody, SELPG antibody, Psgl-1 antibody, Psgl1 antibody, Selp1 antibody, Selpl antibody, selectin P ligand antibody, selectin, platelet (p-selectin) ligand antibody, clasper antibody, SELPLG antibody, Selplg antibody, cla antibody

Background: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.,SELPLG,CD162,CLA,PSGL-1,PSGL1,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Immunology & Inflammation,CD markers,Cardiovascular,SELPLG

Molecular Weight: 43 kDa/44 kDa

Gene ID: 6404

UniProt: Q14242