PDE4D antibody (AA 249-518)

Catalog No. ABIN3022337

Product Details anti-PDE4D Antibody

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Binding Specificity: AA 249-518

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: FKLLQEENCD IFQNLTKKQR QSLRKMVIDI VLATDMSKHM NLLADLKTMV ETKKVTSSGV LLLDNYSDRI QVLQNMVHCA DLSNPTKPLQ LYRQWTDRIM EEFFRQGDRE RERGMEISPM CDKHNASVEK SQVGFIDYIV HPLWETWADL VHPDAQDILD TLEDNREWYQ STIPQSPSPA PDDPEEGRQG QTEKFQFELT LEEDGESDTE KDSGSQVEED TSCSDSKTLC TQDSESTEIP LDEQVEEEAV GEEEESQPEA CVIDDRSPDT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 249-518 of human PDE4D (NP_001184152.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDE4D

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Alternative Name: PDE4D (PDE4D Products)

Synonyms: ACRDYS2 antibody, DPDE3 antibody, HSPDE4D antibody, PDE43 antibody, PDE4DN2 antibody, STRK1 antibody, CMYA2 antibody, MMGL antibody, 9630011N22Rik antibody, Dpde3 antibody, 4732458A06Rik antibody, 9430063L05Rik antibody, C87016 antibody, D130016K21Rik antibody, D3Bwg1078e antibody, Usmg4 antibody, mKIAA0454 antibody, si:dkey-190g11.2 antibody, phosphodiesterase 4D antibody, phosphodiesterase 4D interacting protein antibody, phosphodiesterase 4D, cAMP specific antibody, phosphodiesterase 4D, cAMP-specific antibody, phosphodiesterase 4D interacting protein (myomegalin) antibody, PDE4D antibody, PDE4DIP antibody, pde4d antibody, Pde4dip antibody, Pde4d antibody

Background: This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.,PDE4D,ACRDYS2,DPDE3,HSPDE4D,PDE43,PDE4DN2,STRK1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),PDE4D

Molecular Weight: 23-24 kDa/57-91 kDa

Gene ID: 5144

UniProt: Q08499

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling