PDE4D antibody (AA 249-518)
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- Target See all PDE4D Antibodies
- PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
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Binding Specificity
- AA 249-518
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PDE4D antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- FKLLQEENCD IFQNLTKKQR QSLRKMVIDI VLATDMSKHM NLLADLKTMV ETKKVTSSGV LLLDNYSDRI QVLQNMVHCA DLSNPTKPLQ LYRQWTDRIM EEFFRQGDRE RERGMEISPM CDKHNASVEK SQVGFIDYIV HPLWETWADL VHPDAQDILD TLEDNREWYQ STIPQSPSPA PDDPEEGRQG QTEKFQFELT LEEDGESDTE KDSGSQVEED TSCSDSKTLC TQDSESTEIP LDEQVEEEAV GEEEESQPEA CVIDDRSPDT
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 249-518 of human PDE4D (NP_001184152.1).
- Isotype
- IgG
- Top Product
- Discover our top product PDE4D Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
- Alternative Name
- PDE4D (PDE4D Products)
- Background
- This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.,PDE4D,ACRDYS2,DPDE3,HSPDE4D,PDE43,PDE4DN2,STRK1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),PDE4D
- Molecular Weight
- 23-24 kDa/57-91 kDa
- Gene ID
- 5144
- UniProt
- Q08499
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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