PON2 antibody (AA 1-210)

Catalog No. ABIN3022314

Product Details anti-PON2 Antibody

Target: PON2 (Paraoxonase 2 (PON2))

Binding Specificity: AA 1-210

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MGRLVAVGLL GIALALLGER LLALRNRLKA SREVESVDLP HCHLIKGIEA GSEDIDILPN GLAFFSVGLK FPGLHSFAPD KPGGILMMDL KEEKPRAREL RISRGFDLAS FNPHGISTFI DNDDTVYLFV VNHPEFKNTV EIFKFEEAEN SLLHLKTVKH ELLPSVNDIT AVGPAHFYAT NDHYFSDPFL KYLETYLNLH WANVVYYSPN

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human PON2 (NP_000296.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PON2

Target: PON2 (Paraoxonase 2 (PON2))

Alternative Name: PON2 (PON2 Products)

Synonyms: PON2 antibody, pon1 antibody, MGC53915 antibody, pon2 antibody, 6330405I24Rik antibody, AI481612 antibody, serum paraoxonase/arylesterase 2 antibody, paraoxonase 2 antibody, paraoxonase 2 L homeolog antibody, Serum paraoxonase/arylesterase 2 antibody, LOC100303695 antibody, PON2 antibody, pon2.L antibody, BDBG_00600 antibody, pon2 antibody, Pon2 antibody

Background: This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.,PON2,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Cardiovascular,Lipids,Lipoproteins/Apolipoproteins,PON2

Molecular Weight: 37 kDa/39 kDa

Gene ID: 5445

UniProt: Q15165