NPPA antibody (AA 26-151)

Catalog No. ABIN3022234

Product Details anti-NPPA Antibody

Target: NPPA (Natriuretic Peptide A (NPPA))

Binding Specificity: AA 26-151

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPPA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NPMYNAVSNA DLMDFKNLLD HLEEKMPLED EVVPPQVLSE PNEEAGAALS PLPEVPPWTG EVSPAQRDGG ALGRGPWDSS DRSALLKSKL RALLTAPRSL RRSSCFGGRM DRIGAQSGLG CNSFRY

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-151 of human NPPA (NP_006163.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-NPPA antibody (ABIN3022234)

Kumar, Wang, Liu, Ding, Dong, Zheng, Ye, Liu: "Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms." in: Hypertension (Dallas, Tex. : 1979), Vol. 72, Issue 2, pp. 331-342, (2018) (PubMed).

Target Details for NPPA

Target: NPPA (Natriuretic Peptide A (NPPA))

Alternative Name: NPPA (NPPA Products)

Synonyms: anp antibody, ANF antibody, ANP antibody, Pnd antibody, RATANF antibody, ATFB6 antibody, CDD-ANF antibody, PND antibody, NPPA antibody, Anf antibody, atrial natriuretic peptide antibody, natriuretic peptide A antibody, natriuretic peptide type A antibody, anp antibody, nppa antibody, NPPA antibody, Nppa antibody

Background: The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.,NPPA,ANF,ANP,ATFB6,ATRST2,CDD,CDD-ANF,CDP,PND,NPPA,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Cardiovascular,Blood,Blood Pressure regulation,Heart,Hypertrophy,NPPA

Molecular Weight: 16 kDa

Gene ID: 4878

UniProt: P01160