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Dihydrofolate Reductase antibody (AA 1-187)
DHFR
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Dihydrofolate Reductase Antibody
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Target
See all Dihydrofolate Reductase (DHFR) Antibodies
Dihydrofolate Reductase (DHFR)
Binding Specificity
All epitopes for Dihydrofolate Reductase antibodies
AA 1-187
Reactivity
All reactivities for Dihydrofolate Reductase antibodies
Human
Host
All hosts for Dihydrofolate Reductase antibodies
Rabbit
Clonality
All clonalities for Dihydrofolate Reductase antibodies
Polyclonal
Conjugate
All conjugates for Dihydrofolate Reductase antibodies
This Dihydrofolate Reductase antibody is un-conjugated
Application
All applications for Dihydrofolate Reductase antibodies
Western Blotting (WB), Immunofluorescence (IF)
Sequence
MVGSLNCIVA VSQNMGIGKN GDLPWPPLRN EFRYFQRMTT TSSVEGKQNL VIMGKKTWFS IPEKNRPLKG RINLVLSREL KEPPQGAHFL SRSLDDALKL TEQPELANKV DMVWIVGGSS VYKEAMNHPG HLKLFVTRIM QDFESDTFFP EIDLEKYKLL PEYPGVLSDV QEEKGIKYKF EVYEKND
Cross-Reactivity
Human, Mouse
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human DHFR (NP_000782.1).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Dihydrofolate Reductase
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Target
Dihydrofolate Reductase (DHFR)
Alternative Name
DHFR (DHFR Products )
Background
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene.,DHFR,DHFRP1,DYR,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,Nucleotide metabolism,DHFR
Molecular Weight
15 kDa/21 kDa
Gene ID
1719
UniProt
P00374
Pathways
Mitotic G1-G1/S Phases
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