AT3 antibody, AT3D antibody, ATIII antibody, THPH7 antibody, SERPINC1 antibody, DKFZp470C1733 antibody, AI114908 antibody, At-3 antibody, At3 antibody, ANTITHROMBIN, AT-III antibody, AT-III antibody, serpin family C member 1 antibody, antithrombin-III antibody, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 antibody, SERPINC1 antibody, CpipJ_CPIJ000472 antibody, CpipJ_CPIJ013111 antibody, Serpinc1 antibody
Background
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.,SERPINC1,AT3,AT3D,ATIII,THPH7,Stem Cells,Cardiovascular,Blood,Coagulation,Serum Proteins,SERPINC1